This round has been my friend for a long time. I did the research before purchasing a centerfire 22 rifle and the ballistics and numbers looked best through the 22-250. I've taken a lot of game with mine, everything from crows to whitetails, and with proper shot placement and rage selection it can handle the job. Because I am such an advocate for the 22-250 people often ask me which caliber would be my second choice... secondly I'd lean toward the 243.
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